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Antigenic Specificity | PARP1 |
Clone | monoclonal |
Host Species | Recombinant Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µl (50+ tests) |
Concentration | 1000 µg/ml |
Applications | WB, IP, IHC, ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-Cleaved PARP1 Recombinant Monoclonal Antibody [BLR183J]. PARP1 (Poly-ADP-ribose polymerase 1) is a member of PARP family of enzymes that transfer the ADP-D-ribosyl group of NAD(+) to an acceptor carboxyl group on proteins. PARP1 catalyzes the poly-ADP-ribosylation of histone and non-histone proteins in response to DNA damage. The over-activation of PARP-1 in response to DNA damage has been shown to promote cell and tissue injury. This observation has initiated research into the therapeutic potential of PARP1 inhibitors in the treatment of cancer, cardiovascular disease, and brain injury. |
Immunogen | Epitope: between 215 and 265 |
Other Names | PPOL; PARP-1; PARP; poly [ADP-ribose] polymerase 1; poly(ADP-ribose) synthetase; poly[ADP-ribose] synthase 1; pADPRT-1; poly(ADP-ribosyl)transferase; ARTD1; ADPRT1; ADPRT 1; ADPRT; ADP-ribosyltransferase NAD(+); ADP-ribosyltransferase diphtheria toxin-like 1; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase); NAD(+) ADP-ribosyltransferase 1; poly (ADP-ribose) polymerase family, member 1 |
Gene, Accession # | Gene ID: 142, Accession: NP_001609.1, UniProt: P09874 |
Catalog # | A700-183 |
Price | $482 |
Order / More Info | PARP1 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |