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Antigenic Specificity | VAC14 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, (presumed: rat, bovine) |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-VAC14 Antibody, Affinity Purified. The content of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. VAC14 is a component of a trimolecular complex that tightly regulates the level of PtdIns(3,5)P2. Other components of this complex are the PtdIns(3,5)P2-synthesizing enzyme PIKFYVE (MIM 609414) and the PtdIns(3,5)P2 phosphatase FIG4 (MIM 609390). VAC14 functions as an activator of PIKFYVE (Sbrissa et al., 2007 [PubMed 17556371]) [taken from NCBI Entrez Gene (Gene ID: 55697)]. |
Immunogen | Epitope: between 732 and 782 |
Other Names | Tax1-binding protein 2; TRX; Tax1 (human T-cell leukemia virus type I) binding protein; protein VAC14 homolog; ArPIKfyve; TAX1BP2 |
Gene, Accession # | Gene ID: 55697, Accession: NP_060522.3, UniProt: Q08AM6 |
Catalog # | A304-904A |
Price | $433 |
Order / More Info | VAC14 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |