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Antigenic Specificity | Hepassocin/FGL1 |
Clone | monoclonal |
Host Species | Recombinant Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 10 µl (5+ tests) |
Concentration | 500 µg/ml |
Applications | WB, IP, IHC, ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-Hepassocin/FGL1 Recombinant Monoclonal Antibody [BLR210K]. Hepassocin, also known as Fibrinogen-like 1 (FGL1), is a member of the fibrinogen family whose members share a fibrinogen domain at their C-termini. However, it lacks the platelet-binding site, cross-linking region and thrombin-sensitive site which are necessary for fibrin clot formation. Hepassocin/FGL1 is secreted by hepatocytes and may play a role in the development of hepatocellular carcinomas. Hepassocin/FGL1 is an immune suppressive molecule that inhibits antigen-specific T-cell activation by acting as a major ligand of LAG3 [taken from NCBI Entrez Gene (Gene ID: 2267)]. |
Immunogen | Epitope: residues 18-312 (full length) |
Other Names | LFIRE1; LFIRE-1; HP-041; HFREP-1; HFREP1; hepatocyte-derived fibrinogen-related protein 1; hepatocellular carcinoma-related sequence; hepassocin; fibrinogen-like protein 1; liver fibrinogen-related protein 1 |
Gene, Accession # | Gene ID: 2267, Accession: NP_004458.3, UniProt: Q08830 |
Catalog # | A700-210-T |
Price | $127 |
Order / More Info | Hepassocin/FGL1 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |