Cyclin T1 Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | Cyclin T1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, (presumed: bovine, horse, chimpanzee) |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 100 µl |
| Concentration | 200 µg/ml |
| Applications | WB, IP, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-Cyclin T1 Antibody, Affinity Purified. Cyclin T1 is a regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to productive elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNA Pol II). In case of HIV or SIV infections, Cyclin T1 binds to the transactivation domain of the viral nuclear transcriptional activator, Tat, thereby increasing Tat's affinity for the transactivating response RNA element (TAR RNA) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O60563]. |
| Immunogen | Epitope: between 425 and 475 |
| Other Names | CYCT1; cyclin-T1; HIVE1; MLLT10/CCNT1 fusion; cyclin C-related protein; CDK9-associated C-type protein; CCNT; human immunodeficiency virus type 1 (HIV-1) expression (elevated) 1; Cyclin-T |
| Gene, Accession # | Gene ID: 904, Accession: NP_001231.2, UniProt: O60563 |
| Catalog # | A303-498A |
| Price | $433 |
| Order / More Info | Cyclin T1 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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