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Antigenic Specificity | E2-25K |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, (presumed: bovine) |
Isotype | n/a |
Format | antigen affinity purified |
Size | 10 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-E2-25K Antibody, Affinity Purified. Ubiquitin-conjugating enzyme E2-25 kDa (E2-25K) belongs to the ubiquitin-conjugating enzyme family. E2-25K interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation [taken from NCBI Entrez Gene (Gene ID: 3093)]. |
Immunogen | Epitope: between 150 and 200 |
Other Names | ubiquitin-conjugating enzyme E2-25 KDA; ubiquitin-protein ligase; Ubiquitin-conjugating enzyme E2-25K; ubiquitin-conjugating enzyme E2(25K); ubiquitin-conjugating enzyme E2 K; ubiquitin conjugating enzyme E2K; ubiquitin carrier protein; UBC1; HYPG; huntingtin-interacting protein 2; HIP-2; HIP2; E2-25K; E2(25K); E2 ubiquitin-conjugating enzyme K; ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast); LIG |
Gene, Accession # | Gene ID: 3093, Accession: NP_005330.1, UniProt: P61086 |
Catalog # | A304-125A-T |
Price | $121 |
Order / More Info | E2-25K Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |