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Antigenic Specificity | MKK4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-MKK4 Antibody, Affinity Purified. MAPKK4 (mitogen-activated protein kinase kinase 4) is a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. MAPKK4 is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. Studies in knockout mice suggest that MAPKK4 mediates survival signals in T cell development. It may also be important to liver organogenesis.[taken from NCBI Entrez Gene (GeneID: 6416)]. |
Immunogen | Epitope: between 349 and 399 |
Other Names | SKK1; MKK4; SAPK kinase 1; SAPK/ERK kinase 1; SAPKK1; SAPKK-1; SERK1; MEK4; stress-activated protein kinase kinase 1; SEK1; JNK-activating kinase 1; PRKMK4; MEK 4; JNK-activated kinase 1; c-Jun N-terminal kinase kinase 1; JNKK; JNKK1; MAP kinase kinase 4; MAPK/ERK kinase 4; MAPKK 4; MAPKK4; dual specificity mitogen-activated protein kinase kinase 4 |
Gene, Accession # | Gene ID: 6416, Accession: NP_003001.1, UniProt: P45985 |
Catalog # | A302-658A |
Price | $433 |
Order / More Info | MKK4 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |