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Antigenic Specificity | PAK2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 10 µl |
Concentration | 200 µg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-PAK2 Antibody, Affinity Purified. PAK2 (p21-activated kinase 2) is part of the family of PAK serine/threonine p21-activating protein kinases involved in cell survival, migration, and invasion. The PAK family of proteins mediates signals from extracellular stimuli to the cytoplasm and nucleus via its association with the small GTP-binding proteins Cdc42 and Rac. PAK2 has been shown to play a specific role in apoptosis and cytoskeletal dynamics. During caspase-mediated apoptosis, PAK2 is cleaved and the C-terminal myristoylated fragment mediates cell death and actin reorganization via the JNK signaling pathway. |
Immunogen | Epitope: between 125 and 175 |
Other Names | p58; serine/threonine-protein kinase PAK 2; S6/H4 kinase; PAKgamma; gamma-PAK; PAK-2; p21-activated kinase 2; p21 protein (Cdc42/Rac)-activated kinase 2; p21 (CDKN1A)-activated kinase 2; PAK65 |
Gene, Accession # | Gene ID: 5062, Accession: NP_002568.2, UniProt: Q13177 |
Catalog # | A301-264A-T |
Price | $121 |
Order / More Info | PAK2 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |