STAT3, Phospho (Y705) Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | STAT3, Phospho (Y705) |
| Clone | monoclonal |
| Host Species | Recombinant Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | purified |
| Size | 100 µl |
| Concentration | 1000 µg/ml |
| Applications | WB, IP, IHC, ICC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-STAT3-pY705 Recombinant Monoclonal Antibody [BLR231K]. STAT3 (signal transducer and activator of transcription 3) is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein [taken from NCBI Entrez Gene (GeneID:6774)]. |
| Immunogen | Epitope: surrounding Tyrosine 705 |
| Other Names | acute-phase response factor; ADMIO; ADMIO1; APRF; DNA-binding protein APRF; HIES; signal transducer and activator of transcription 3 |
| Gene, Accession # | Gene ID: 6774, Accession: NP_644805.1, UniProt: P40763 |
| Catalog # | A700-231CF |
| Price | $794 |
| Order / More Info | STAT3, Phospho (Y705) Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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