STAT3 Antibody from FORTIS LIFE SCIENCES

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Antigenic SpecificitySTAT3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, (presumed: mouse, rat, bovine, porcine)
Isotypen/a
Formatantigen affinity purified
Size100 µl
Concentration1000 µg/ml
ApplicationsIP
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DescriptionRabbit anti-STAT3 Antibody, Affinity Purified. STAT3 (signal transducer and activator of transcription 3) is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein [taken from NCBI Entrez Gene (GeneID:6774)].
ImmunogenEpitope: between 675 and 725
Other Namesacute-phase response factor; ADMIO; ADMIO1; APRF; DNA-binding protein APRF; HIES; signal transducer and activator of transcription 3
Gene, Accession #Gene ID: 6774, Accession: NP_644805.1, UniProt: P40763
Catalog #A302-405A
Price$433
Order / More InfoSTAT3 Antibody from FORTIS LIFE SCIENCES
Product Specific Referencesn/a
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
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