CSTF2T/TauCSTF64 Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | CSTF2T/TauCSTF64 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 10 µl |
| Concentration | 1000 µg/ml |
| Applications | IP |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-CSTF2T/TauCSTF64 Antibody, Affinity Purified. CSTF2T, also known as tauCSTF-64, is a paralog of CstF-64, a component of the cleavage stimulation factor (CstF) that processes 3'-end formation and polyadenylation of mRNAs. The human CSTF2T/TauCSTF64 gene is located at 10q22-23, a site associated with neurological problems and male infertility. CSTF2T is expressed in all tissues and throughout meiosis in male germ cells. CstF-64 is also expressed ubiquitously; however because it is located on the X chromosome, its expression is temporarily silenced in germ cells by meiotic sex chromosome inactivation. During this inactivation, it is hypothesized that CSTF2T/TauCSTF64 can compensate for the loss of CstfF-64 expression. Recently, targeted disruption of CSTF2T/TauCSTF64 in mice has been shown to cause aberrant spermatogenesis and infertility providing more evidence for its importance in spermatogenesis. |
| Immunogen | Epitope: between 225 and 275 |
| Other Names | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau; CstF-64T; CSTF 64 kDa subunit tau variant; tauCstF-64; cleavage stimulation factor, 3' pre-RNA, subunit 2, tau; cleavage stimulation factor subunit 2 tau variant; Cleavage stimulation factor 64 kDa subunit tau variant; cleavage stimulation factor 64 kDa subunit tau; CF-1 64 kDa subunit tau variant; CF-1 64 kDa subunit tau; CSTF 64 kDa subunit tau; cleavage stimulation factor subunit 2, tau |
| Gene, Accession # | Gene ID: 23283, Accession: NP_056050.1, UniProt: Q9H0L4 |
| Catalog # | A301-486A-T |
| Price | $121 |
| Order / More Info | CSTF2T/TauCSTF64 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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