MDR1/ABCB1 Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | MDR1/ABCB1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 100 µl |
| Concentration | 1000 µg/ml |
| Applications | WB, IP |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-MDR1/ABCB1 Antibody, Affinity Purified. Multidrug resistance protein 1 (MDR1) is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). MDR1 is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. MDR1 is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. MDR1 also functions as a transporter in the blood-brain barrier [taken from NCBI Entrez Gene (Gene ID: 5243)]. |
| Immunogen | Epitope: between 1 and 50 |
| Other Names | GP170; ABC20; P-GP; P-glycoprotein 1; P glycoprotein; multidrug resistance protein 1; MDR1; doxorubicin resistance; colchicin sensitivity; CLCS; CD243; CD antigen CD243; ATP-binding cassette sub-family B member 1; PGY1; ATP-binding cassette, sub-family B (MDR/TAP), member 1 |
| Gene, Accession # | Gene ID: 5243, Accession: NP_000918.2, UniProt: P08183 |
| Catalog # | A303-625A |
| Price | $433 |
| Order / More Info | MDR1/ABCB1 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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