SPTY2D1 Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | SPTY2D1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, (presumed: mouse) |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 100 µl |
| Concentration | 1000 µg/ml |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-SPTY2D1 Antibody, Affinity Purified. SPT2, Suppressor of Ty (SPTY2D1) is a histone chaperone that stabilizes pre-existing histone tetramers and regulates replication-independent histone exchange on chromatin (PubMed:26109053). It is required for normal chromatin refolding in the coding region of transcribed genes, and for the suppression of spurious transcription (PubMed:26109053). SPTY2D1 binds DNA and histones and promotes nucleosome assembly (in vitro) (PubMed:23378026, PubMed:26109053). It facilitates formation of tetrameric histone complexes containing histone H3 and H4 (PubMed:26109053). SPTY2D1 modulates RNA polymerase 1-mediated transcription (By similarity) and binds DNA, with a preference for branched DNA species, such as Y-form DNA and Holliday junction DNA (PubMed:23378026) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q68D10]. |
| Immunogen | Epitope: between 75 and 125 |
| Other Names | Protein KU002155; SPT2, Suppressor of Ty, domain containing 1; SPT2 domain-containing protein 1; protein SPT2 homolog; Spt2 |
| Gene, Accession # | Gene ID: 144108, Accession: NP_919261.2, UniProt: Q68D10 |
| Catalog # | A304-996A |
| Price | $433 |
| Order / More Info | SPTY2D1 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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