Edit |   |
---|---|
Antigenic Specificity | RNF169 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 10 µl |
Concentration | 1000 µg/ml |
Applications | IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-RNF169 Antibody, Affinity Purified. RING finger protein 169 (RNF169) is a probable E3 ubiquitin-protein ligase that acts as a negative regulator of the repair of double-strand breaks (DSBs) following DNA damage. RNF169 is recruited to DSB repair sites by recognizing and binding ubiquitin catalyzed by RNF168 and competes with TP53BP1 and BRCA1 for association with RNF168-modified chromatin, thereby acting as a negative regulator of DSB repair [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8NCN4]. |
Immunogen | Epitope: between 200 and 250 |
Other Names | E3 ubiquitin-protein ligase RNF169; RING finger protein 169; RING-type E3 ubiquitin transferase RNF169 |
Gene, Accession # | Gene ID: 254225, Accession: NP_001092108.1, UniProt: Q8NCN4 |
Catalog # | A304-097A-T |
Price | $121 |
Order / More Info | RNF169 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |