RENT2 Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | RENT2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 100 µl |
| Concentration | 1000 µg/ml |
| Applications | WB, IP |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-RENT2 Antibody, Affinity Purified. Regulator of nonsense transcripts 2 (RENT2), also known as UPF2, is involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC). RENT2 is recruited by UPF3B associated with the EJC core at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF3B, RENT2 stimulates both ATPase and RNA helicase activities of UPF1. RENT2 binds spliced mRNA [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9HAU5]. |
| Immunogen | Epitope: between 1 and 50 |
| Other Names | FRS2/UPF2/LEMD3 fusion; smg-3; yeast Upf2p homolog; up-frameshift suppressor 2 homolog; UPF2 regulator of nonsense transcripts homolog; smg-3 homolog, nonsense mediated mRNA decay factor; regulator of nonsense transcripts 2; nonsense mRNA reducing factor 2; LEMD3/UPF2 fusion; HUPF2; RENT2 |
| Gene, Accession # | Gene ID: 26019, Accession: NP_056357.1, UniProt: Q9HAU5 |
| Catalog # | A303-929A |
| Price | $433 |
| Order / More Info | RENT2 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
FORTIS LIFE SCIENCES
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