cAbl Antibody from FORTIS LIFE SCIENCES

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Antigenic SpecificitycAbl
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size100 µl
Concentration1000 µg/ml
ApplicationsIP, IHC, ICC-IF
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DescriptionRabbit anti-cAbl Antibody, Affinity Purified. c-Abl is the human cellular homolog of a the v-Abl viral oncogene. v-Abl was originally discovered as a mouse cell-derived sequence in the genome of the Abelson murine leukemia virus (A-MuLV), a transforming retrovirus isolated by the laboratory of Dr. H.T. Abelson. c-Abl is a tyrosine kinase from the Src-family of tyrosine kinases that localizes to both the cytoplasm and nucleus. It bears an SH2 (src-homology 2) and SH3 (src-homology 3) domain responsible for mediating c-Abl protein-protein interactions. c-Abl is implicated to play a role in multiple cellular processes such as cell cycle checkpoint signaling, apoptosis, cell differentiation, cell adhesion, and transcriptional regulation. Chromosomal translocations involving the c-Abl gene are associated with human leukemias.
ImmunogenEpitope: between 850 and 900
Other Namesp150; proto-oncogene c-Abl; proto-oncogene tyrosine-protein kinase ABL1; tyrosine-protein kinase ABL1; v-abl; v-abl Abelson murine leukemia viral oncogene homolog 1; JTK7; c-ABL; Abelson murine leukemia viral oncogene homolog 1; c-abl oncogene 1, receptor tyrosine kinase; c-ABL1; bcr/c-abl oncogene protein; bcr/abl; ABL; Abelson tyrosine-protein kinase 1; CHDSKM
Gene, Accession #Gene ID: 25, Accession: NP_005148.2, UniProt: P00519
Catalog #A301-661A
Price$433
Order / More InfocAbl Antibody from FORTIS LIFE SCIENCES
Product Specific Referencesn/a
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