Mdc1/Nfbd1 Antibody from FORTIS LIFE SCIENCES
Search, find, compare suppliers for anti-Mdc1/Nfbd1 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Mdc1/Nfbd1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 100 µl |
| Concentration | 1000 µg/ml |
| Applications | IP |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-Mdc1/Nfbd1 Antibody, Affinity Purified. Mediator of DNA damage checkpoint protein 1 (Mdc1) is required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. It may serve as a scaffold for the recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage marked by 'Ser-139' phosphorylation of histone H2AFX. It is also required for downstream events subsequent to the recruitment of these proteins. These include phosphorylation and activation of the ATM, CHEK1 and CHEK2 kinases, and stabilization of TP53 and apoptosis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q5PSV9]. |
| Immunogen | Epitope: between 900 and 950 |
| Other Names | mKIAA0170; mediator of DNA damage checkpoint protein 1; Nfbd1; AA413496; 6820401C03; mediation of DNA damage checkpoint 1 |
| Gene, Accession # | Gene ID: 240087, Accession: NP_055456.1, UniProt: Q5PSV9 |
| Catalog # | A304-843A |
| Price | $433 |
| Order / More Info | Mdc1/Nfbd1 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
1440 Main Street, Suite 300
Waltham MA 02451
P: 800.338.9579
info@fortislife.com
https://www.fortislife.com
Profile of FORTIS LIFE SCIENCES