CD45RO Antibody from FORTIS LIFE SCIENCES

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Antigenic SpecificityCD45RO
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
Isotypen/a
Formatpurified
Size10 µl (5+ tests)
Concentration50 µg/ml
ApplicationsWB, IHC, ICC, IHC-IF, Flow Cyt, mIF
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DescriptionMouse anti-CD45RO Monoclonal Antibody, Purified [UCHL-1]. CD45RO is also known as protein tyrosine phosphatase receptor type C (PTPRC). It is a protein tyrosine phosphatase required for T-cell activation through the antigen receptor. CD45RO acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, CD45RO recruits and dephosphorylates SKAP1 and FYN. It also dephosphorylates LYN, and thereby modulates LYN activity (By similarity)[taken from UniProtKB (Entry: P08575)].
ImmunogenCultured T-cells from an IL-2-dependent T-cell line (CA1)
Other NamesL-CA; protein tyrosine phosphatase, receptor type, c polypeptide; T200 leukocyte common antigen; T200 glycoprotein; receptor-type tyrosine-protein phosphatase C; LY5; Leukocyte common antigen; GP180; CD45R; B220; CD45 antigen; LCA; CD45; CD antigen CD45; T200
Gene, Accession #Gene ID: 5788, Accession: NP_563578.2, UniProt: P08575
Catalog #A500-020A-T
Price$127
Order / More InfoCD45RO Antibody from FORTIS LIFE SCIENCES
Product Specific Referencesn/a
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
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