Edit |   |
---|---|
Antigenic Specificity | CD45RO |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 10 µl (5+ tests) |
Concentration | 50 µg/ml |
Applications | WB, IHC, ICC, IHC-IF, Flow Cyt, mIF |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti-CD45RO Monoclonal Antibody, Purified [UCHL-1]. CD45RO is also known as protein tyrosine phosphatase receptor type C (PTPRC). It is a protein tyrosine phosphatase required for T-cell activation through the antigen receptor. CD45RO acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, CD45RO recruits and dephosphorylates SKAP1 and FYN. It also dephosphorylates LYN, and thereby modulates LYN activity (By similarity)[taken from UniProtKB (Entry: P08575)]. |
Immunogen | Cultured T-cells from an IL-2-dependent T-cell line (CA1) |
Other Names | L-CA; protein tyrosine phosphatase, receptor type, c polypeptide; T200 leukocyte common antigen; T200 glycoprotein; receptor-type tyrosine-protein phosphatase C; LY5; Leukocyte common antigen; GP180; CD45R; B220; CD45 antigen; LCA; CD45; CD antigen CD45; T200 |
Gene, Accession # | Gene ID: 5788, Accession: NP_563578.2, UniProt: P08575 |
Catalog # | A500-020A-T |
Price | $127 |
Order / More Info | CD45RO Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |