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Antigenic Specificity | ACC1/ACC-alpha |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, (presumed: mouse, rat, sheep, bovine) |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-ACC1/ACC-alpha Antibody, Affinity Purified. ACC1/ACC-alpha catalyzes the carboxylation of acetyl-CoA to malonyl-CoA in the enzymatic pathway of long-chain fatty-acid synthesis. ACC1/ACC-alpha has been identified as a partner of BRCA1. Through this interaction, ACC1/ACC-alpha may contribute to the tumor suppressor activity of BRCA1 as demonstrated by the finding that disruption of this interaction increases lipid synthesis in mammary epithelial cells. In this context, lipogenesis has been closely linked to tumorigenesis and ACC1/ACC-alpha has been found to be highly expressed in human breast carcinomas. |
Immunogen | Epitope: between 2333 and C-term |
Other Names | ACC; Biotin carboxylase; acetyl-Coenzyme A carboxylase alpha; acetyl-CoA carboxylase 1; ACC-alpha; ACC1; ACACAD; ACAC; ACCA |
Gene, Accession # | Gene ID: 31, Accession: NP_942135.1, UniProt: Q13085 |
Catalog # | A300-987A |
Price | $433 |
Order / More Info | ACC1/ACC-alpha Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |