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Antigenic Specificity | MED12 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 10 µl |
Concentration | 250 µg/ml |
Applications | IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-MED12 IHC Antibody, Affinity Purified. MED12 is a component of the multisubunit mediator complex that functions as an interface between gene-specific transcription factors and the RNA Pol II/general transcription factor machinery. The mediator complex was first identified as a coactivator of the thyroid hormone receptor and has since been observed to function as a coactivator of a variety of transcription factors. In this context, MED12 interaction with beta-catenin has been shown to be required for Wnt-signaling dependent transcription. |
Immunogen | Epitope: between 2150 and C-term |
Other Names | OHDOX; trinucleotide repeat-containing gene 11 protein; trinucleotide repeat containing 11 (THR-associated protein, 230 kDa subunit); TRAP230; TNRC11; thyroid hormone receptor-associated protein, 230 kDa subunit; thyroid hormone receptor-associated protein complex 230 kDa component; putative mediator subunit 12; OPA-containing protein; OKS; FGS1; activator-recruited cofactor 240 kDa component; ARC240; OPA1; CAGH45; mediator of RNA polymerase II transcription, subunit 12 homolog; HOPA; human opposite paired; MED12S; Mediator complex subunit 12; mediator of RNA polymerase II transcription subunit 12; CAG repeat protein 45 |
Gene, Accession # | Gene ID: 9968, Accession: NP_005111.2, UniProt: Q93074 |
Catalog # | IHC-00180-T |
Price | $121 |
Order / More Info | MED12 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |