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Antigenic Specificity | NF-kappaB1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 200 µg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-NF-kappaB1 Antibody, Affinity Purified. The NFKB1 gene encodes a 105 kDa protein that can undergo co-translational processing to also yield a 50 kDa protein. The 50 kDa protein is also known as NF-kappa B1/p50 and is one of five monomeric subunits that are part of the Rel family of proteins that dimerize to form the NF-kappa B (nuclear factor that binds the kappa immunoglobulin light chain gene enhancer) transcription factor. Members of the Rel family of proteins include NF-kappa B1/p50, NF-kappa B2/p52, RelA/p65, c-Rel, and RelB. The 105 kDa product is also known as p105 or I kappa B gamma. p105/I kappa B gamma has been shown to function as an inhibitor protein that interacts with NF-kappa B and inhibit its DNA binding activity. p105/I kappa B gamma is a member of the I kappa B family of proteins which includes I kappa B-beta, I kappa B-delta/NF-kappa B2/p100, I kappa B-gamma/NF-kappa B1/p105, I kappa B-epsilon, I kappa B-zeta, and Bcl3. The classical description of the NF-kappa B transcription factor is a transcription factor that reprograms gene expression of the immune system in response to injury, infection, and stress. |
Immunogen | Epitope: between 918 and 968 |
Other Names | NFKB-p105; p50; p105; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; nuclear factor NF-kappa-B p50 subunit; nuclear factor NF-kappa-B p105 subunit; NFKB-p50; NF-kB1; DNA-binding factor KBF1; NF-kappa-B1; NF-kappaB; NFkappaB; KBF1; EBP-1; NF-kappabeta; CVID12; nuclear factor kappa-B DNA binding subunit |
Gene, Accession # | Gene ID: 4790, Accession: NP_003989.2, UniProt: P19838 |
Catalog # | A301-820A |
Price | $433 |
Order / More Info | NF-kappaB1 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |