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Antigenic Specificity | CD25/IL-2R alpha |
Clone | monoclonal |
Host Species | Recombinant Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | IHC, ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-CD25/IL-2R alpha Recombinant Monoclonal Antibody [BLR158J]. The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. The IL2 receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. [taken from NCBI Entrez Gene (Gene ID: 3559)]. |
Immunogen | Epitope: between 222 and 272 (C-term) |
Other Names | IMD41; IL-2 receptor subunit alpha; TCGFR; TAC antigen; p55; interleukin-2 receptor subunit alpha; interleukin 2 receptor, alpha; IL-2-RA; CD antigen CD25; IL2R; IL-2R subunit alpha; IDDM10; CD25; IL2-RA |
Gene, Accession # | Gene ID: 3559, Accession: NP_000408.1, UniProt: P01589 |
Catalog # | A700-158CF |
Price | $794 |
Order / More Info | CD25/IL-2R alpha Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |