MCAK Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | MCAK |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 10 µl |
| Concentration | 1000 µg/ml |
| Applications | IP |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-MCAK Antibody, Affinity Purified. Kinesin activity has been linked to various cellular functions such as vesicle transport, mitotic spindle formation, chromosome segregation, chromosome congression, and cytokinesis. Structurally, all kinesins contain a motor domain with microtubule and nucleotide binding sites that utilize ATP to target cargo along microtubule filaments. MCAK (Mitotic Centromere-Associated Kinesin) is the founding member of kinesin-13 proteins. There are 3 independent genes coding for kinesin-13 proteins kif2a, kif2b, and kif2c (MCAK). Instead of functioning as a translocator of microtubules MCAK is a depolymerizer that is primarily responsible for releasing improper microtubule-kinetochore attachments during cell division. |
| Immunogen | Epitope: between 550 and 600 |
| Other Names | Knsl6; X83316; mitotic centromere-associated kinesin; MCAK; kinesin-like protein KIF2C; kinesin-like 6; 4930402F02Rik; ESTM5 |
| Gene, Accession # | Gene ID: 73804, Accession: NP_608301.3, UniProt: Q922S8 |
| Catalog # | A300-922A-T |
| Price | $121 |
| Order / More Info | MCAK Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
FORTIS LIFE SCIENCES
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