SMARCAL1 Antibody from FORTIS LIFE SCIENCES
Search, find, compare suppliers for anti-SMARCAL1 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | SMARCAL1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, (presumed: bovine) |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 100 µl |
| Concentration | 200 µg/ml |
| Applications | WB, IP |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-SMARCAL1 Antibody, Affinity Purified. The SMARCs (SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin), and BAFs (BRG1-associated factors), have been identified as components of the mammalian SWI/SNF-like chromatin-remodeling protein complexes. These multi-protein complexes are proposed to function as ATP-driven motors that translocate along DNA and destabilize nucleosomal structures to facilitate transcription factor binding. SMARCAL1 is a member of the SNF2 family. SMARCAL1 is also known as human hep-related protein (HARP) due to its sequence identity with the E. coli RNA polymerase-binding protein HepA. It has been determined that mutations in SMARCAL1 are the cause of Schimke immuno-osseous dysplasia (SIOD), an autosomal-recessive disorder characterized by spondyloepiphyseal dysplasia, renal dysfunction, facial dysmorphism, and T-cell immunodeficiency. The pleiotropic characteristics of SIOD indicate an important role for SMARCAL1 in the regulation of multiple genes that influence the proliferation of chondrocytes, lymphocytes, and spermatozytes, as well as the development of cardiomyocytes and vascular homeostasis. |
| Immunogen | Epitope: between 904 and 954 |
| Other Names | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1; sucrose nonfermenting protein 2-like 1; SMARCA-like protein 1; HepA-related protein; ATP-driven annealing helicase; HARP; HHARP |
| Gene, Accession # | Gene ID: 50485, Accession: NP_054859.2, UniProt: Q9NZC9 |
| Catalog # | A301-616A |
| Price | $433 |
| Order / More Info | SMARCAL1 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
1440 Main Street, Suite 300
Waltham MA 02451
P: 800.338.9579
info@fortislife.com
https://www.fortislife.com
Profile of FORTIS LIFE SCIENCES
Return to Antibodies