Mel-18 Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | Mel-18 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 100 µl |
| Concentration | 1000 µg/ml |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-Mel-18 Antibody, Affinity Purified. Mel18 is a transcriptional repressor and binds specifically to the DNA sequence 5'-GACTNGACT-3'. Mel-18 is a component of a polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. Mel-18 has tumor suppressor activity. Mel-18 plays a role in control of cell proliferation and/or neural cell development, and also plays a role in antero-posterior specification of the axial skeleton and negative regulation of the self-renewal activity of hematopoietic stem cells. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ P35227]. |
| Immunogen | Epitope: between 125 and 175 |
| Other Names | ZNF144; zinc finger protein 144; RNF110; ring finger protein 110; polycomb group RING finger protein 2; DNA-binding protein Mel-18; MEL-18 |
| Gene, Accession # | Gene ID: 7703, Accession: NP_009075.1, UniProt: P35227 |
| Catalog # | A303-580A |
| Price | $433 |
| Order / More Info | Mel-18 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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