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Antigenic Specificity | PP2A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, (presumed: rat) |
Isotype | n/a |
Format | antigen affinity purified |
Size | 10 µl |
Concentration | 200 µg/ml |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-PP2A Antibody, Affinity Purified. PP2A is a major serine/threonine phosphatase that is implicated in the negative control of cell cycle progression. PP2A encodes the beta isoform of the catalytic subunit (PP2CB). Chk2 has been shown to be negatively regulated and dephosphorylated by PP2A. Several proteins have been shown to associate with PP2A and regulate its activity such as eRF1, Hox11, CK2, and Igbp1/alpha4. Rapamycin has been shown to dissociate PP2A from alpha-4 and inhibit proliferation. This result suggests an alternative positive regulatory role of PP2A in cell proliferation. |
Immunogen | Epitope: between 1 and 50 |
Other Names | protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform; serine/threonine-protein phosphatase 2A catalytic subunit beta isoform; serine/threonine protein phosphatase 2A, catalytic subunit, beta isoform; protein phosphatase type 2A catalytic subunit; testicular tissue protein Li 146; protein phosphatase 2A catalytic subunit, beta isoform; PP2CB; PP2A-beta; PP2Abeta; protein phosphatase 2, catalytic subunit, beta isozyme; protein phosphatase 2, catalytic subunit, beta isoform |
Gene, Accession # | Gene ID: 5516, Accession: NP_004147.1, UniProt: P62714 |
Catalog # | A300-731A-T |
Price | $121 |
Order / More Info | PP2A Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |