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Antigenic Specificity | BRCA2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-BRCA2 Antibody, Affinity Purified. BRCA2 was identified as a gene with germline mutations that predisposes women to breast cancer. An important function of BRCA2 involves its direct interaction with RAD51 and the process of homologous recombination in DNA double strand break repair. BRCA2 and BRCA1 primary sequences are not similar; however the proteins exhibit similar patterns of expression and sub-cellular localization. Although the phenotype of disruptions of BRCA2 is similar to BRCA1, BRCA2 appears to possess functions distinct from BRCA1. |
Immunogen | Epitope: between 3350 and C-term |
Other Names | FAD1; FANCD; Fanconi anemia group D1 protein; mutant BRCA2; PNCA2; XRCC11; FANCD1; FAD; truncated breast cancer 2; BROVCA2; breast cancer type 2 susceptibility protein; BRCA1/BRCA2-containing complex, subunit 2; breast cancer 2, early onset; GLM3; breast cancer 2 tumor suppressor; breast and ovarian cancer susceptibility protein 2; breast and ovarian cancer susceptibility gene, early onset; BRCC2; FACD |
Gene, Accession # | Gene ID: 675, Accession: NP_000050.1, UniProt: P51587 |
Catalog # | A300-005A |
Price | $433 |
Order / More Info | BRCA2 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |