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Antigenic Specificity | PSMD4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, (presumed: bovine) |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-PSMD4 Antibody, Affinity Purified. PSMD4 [proteasome (prosome, macropain) 26S subunit, non-ATPase, 4] is a non-ATPase subunit of the 19S regulator lid. The 19S regulator and 20S core complexes make up the 26S proteasome which is a multicatalytic proteinase complex with a highly ordered structure. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides [taken from NCBI Entrez Gene (Gene ID: 5710)]. |
Immunogen | Epitope: between 250 and 300 |
Other Names | multiubiquitin chain-binding protein; S5a/antisecretory factor protein; S5A; Rpn10; proteasome (prosome, macropain) 26S subunit, non-ATPase, 4; MCB1; ASF; angiocidin; 26S proteasome non-ATPase regulatory subunit 4; AF-1; AF; 26S proteasome regulatory subunit S5A; 26S proteasome regulatory subunit RPN10; antisecretory factor 1; pUB-R5 |
Gene, Accession # | Gene ID: 5710, Accession: NP_002801.1, UniProt: P55036 |
Catalog # | A303-855A |
Price | $433 |
Order / More Info | PSMD4 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |