Edit |   |
---|---|
Antigenic Specificity | ARMS |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-ARMS Antibody, Affinity Purified. Ankyrin repeat-rich membrane-spanning protein (ARMS) is also known as Kinase D-interacting substrate of 220 kDa (KIDINS220). ARMS Promotes prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Arms may play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. ARMS may play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration. ARMS has also been shown to modulate stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9ULH0]. |
Immunogen | Epitope: between 1400 and 1450 |
Other Names | ankyrin repeat-rich membrane-spanning protein; ARMS; kinase D-interacting substrate 220kDa; kinase D-interacting substrate of 220 kDa; SINO |
Gene, Accession # | Gene ID: 57498, Accession: NP_065789.1, UniProt: Q9ULH0 |
Catalog # | A303-002A |
Price | $433 |
Order / More Info | ARMS Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |