Edit |   |
---|---|
Antigenic Specificity | Drosha |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 10 µl |
Concentration | 200 µg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-Drosha Antibody, Affinity Purified. Drosha is one of three human RNase III enzymes (Drosha, Dicer, and Argonaute) that play a diverse role in the processing and maturation of RNA. Drosha, along with DGCR8 (DeGeorge Syndrome Chromomsomal Region 8, also known as Pasha in C. elegans and D. melanogaster) is a component of the Microprocessor complex. In this complex, Drosha functions as a double-stranded endoribonuclease critical to the first step in the processing of human microRNAs. During this step, Drosha is responsible for cleaving pri-miRNA to yield hairpin-shaped pre-miRNA for futher processing by the cytoplasmic RNase III enzyme, Dicer. |
Immunogen | Epitope: between 1324 and 1374 |
Other Names | RANSE3L; ribonuclease 3; RNASEN; RNASE3L; RNase III; RN3; ribonuclease type III, nuclear; drosha, double-stranded RNA-specific endoribonuclease; putative protein p241 which interacts with transcription factor Sp1; putative ribonuclease III; Protein Drosha; p241; nuclear RNase III Drosha; HSA242976; ETOHI2; Ribonuclease III |
Gene, Accession # | Gene ID: 29102, Accession: NP_037367.3, UniProt: Q9NRR4 |
Catalog # | A301-886A-T |
Price | $121 |
Order / More Info | Drosha Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |