TBC1D23 Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | TBC1D23 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, (presumed: mouse, zebrafish, Xenopus laevis, chicken, orangutan) |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 10 µl |
| Concentration | 1000 µg/ml |
| Applications | WB, IP |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-TBC1D23 Antibody, Affinity Purified. TBC1D23 is a putative Rab GTPase-activating protein which plays a role in vesicular trafficking and is involved in endosome-to-Golgi trafficking. Acts as a bridging protein by binding simultaneously to golgins, including GOLGA1 and GOLGA4, located at the trans-Golgi, and to the WASH complex, located on endosome-derived vesicles. Together with WDR11 complex facilitates the golgin-mediated capture of vesicles generated using AP-1. TBC1D23 also plays a role in brain development, including in cortical neuron positioning. May also be important for neurite outgrowth, possibly through its involvement in membrane trafficking and cargo delivery, 2 processes that are essential for axonal and dendritic growth. May act as a general inhibitor of innate immunity signaling, strongly inhibiting multiple TLR and dectin/CLEC7A-signaling pathways. Does not alter initial activation events, but instead affects maintenance of inflammatory gene expression several hours after bacterial lipopolysaccharide (LPS) challenge. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NUY8]. |
| Immunogen | Epitope: between 525 and 575 |
| Other Names | PCH11; TBC1 domain family member 23; NS4ATP1; HCV nonstructural protein 4A-transactivated protein 1; HCV non-structural protein 4A-transactivated protein 1 |
| Gene, Accession # | Gene ID: 55773, Accession: NP_060779.2, UniProt: Q9NUY8 |
| Catalog # | A305-870A-T |
| Price | $121 |
| Order / More Info | TBC1D23 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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