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Antigenic Specificity | PUF60 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, (presumed: orangutan) |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 200 µg/ml |
Applications | WB, IP, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-PUF60 Antibody, Affinity Purified. Poly-U binding splicing factor 60KDa (PUF60) is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. PUF60 is implicated in the xeroderma pigmentosum disorder [taken from NCBI Entrez Gene (Gene ID: 22827)]. |
Immunogen | Epitope: between 1 and 50 |
Other Names | pyrimidine tract binding splicing factor; Siah-BP1; SIAHBP1; Siah-binding protein 1; Siah binding protein 1; RoBPI; RoBP1; 60 kDa poly(U)-binding-splicing factor; Ro ribonucleoprotein-binding protein 1; poly(U)-binding-splicing factor PUF60; poly(U) binding splicing factor 60KDa; FUSE-binding protein-interacting repressor; FIR; FBP-interacting repressor; FBP interacting repressor; VRJS; Ro-binding protein 1 |
Gene, Accession # | Gene ID: 22827, Accession: NP_510965.1, UniProt: Q9UHX1 |
Catalog # | A302-817A |
Price | $433 |
Order / More Info | PUF60 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |