NIPA Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | NIPA |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, (presumed: orangutan) |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 100 µl |
| Concentration | 1000 µg/ml |
| Applications | IP |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-NIPA Antibody, Affinity Purified. Nuclear-interacting partner of ALK (NIPA) is an essential component of an SCF-type E3 ligase complex, SCF(NIPA), a complex that controls mitotic entry by mediating ubiquitination and subsequent degradation of cyclin B1 (CCNB1). Its cell-cycle-dependent phosphorylation regulates the assembly of the SCF(NIPA) complex, restricting CCNB1 ubiquitination activity to interphase. Its inactivation results in nuclear accumulation of CCNB1 in interphase and premature mitotic entry. NIPA may have an antiapoptotic role in NPM-ALK-mediated signaling events [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q86WB0]. |
| Immunogen | Epitope: between 1 and 50 |
| Other Names | nuclear-interacting partner of ALK; hNIPA; Zinc finger C3HC-type protein 1; Nuclear-interacting partner of anaplastic lymphoma kinase; hematopoietic stem/progenitor cell protein 216; HSPC216; NIPA; nuclear interacting partner of anaplastic lymphoma kinase (ALK) |
| Gene, Accession # | Gene ID: 51530, Accession: NP_057562.3, UniProt: Q86WB0 |
| Catalog # | A302-941A |
| Price | $433 |
| Order / More Info | NIPA Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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