RLIP76 Antibody from FORTIS LIFE SCIENCES

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Antigenic SpecificityRLIP76
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size100 µl
Concentration1000 µg/ml
ApplicationsWB, IP
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DescriptionRabbit anti-RLIP76 Antibody, Affinity Purified. 76 kDa Ral-interacting protein (RLIP76) can activate, specifically, hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. RLIP76 mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. It can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. It serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15311].
ImmunogenEpitope: between 605 and 655
Other NamesRalBP1; RLIP76; RLIP1; ral-interacting protein 1; ralA-binding protein 1; DNP-SG ATPase; dinitrophenyl S-glutathione ATPase; 76 kDa Ral-interacting protein; RIP1
Gene, Accession #Gene ID: 10928, Accession: NP_006779.1, UniProt: Q15311
Catalog #A304-498A
Price$433
Order / More InfoRLIP76 Antibody from FORTIS LIFE SCIENCES
Product Specific Referencesn/a
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
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