AKAP8/AKAP95 Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | AKAP8/AKAP95 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 10 µl |
| Concentration | 100 µg/ml |
| Applications | IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-AKAP8/AKAP95 IHC Antibody, Affinity Purified. AKAP8/AKAP95 has been characterized as a 95 kDa protein kinase A (PKA)-anchoring protein and regulatory subunit of PKA that functions to recruit the condensin complex for chromosome condensation during mitosis. A role in DNA replication has also been demonstrated through its interaction with the pre-replication complex component, MCM2 (mini-chromosome maintenance 2). Inhibition of AKAP8/AKAP95 association with MCM2 inhibits replication initiation and elongation in vitro. AKAP8/AKAP95 has also been shown to be involved in apoptosis. KAP8/AKAP95 associates with caspase 3 and serves as a carrier to transport caspase 3 from the cytoplasm to the nucleus to induce morphological changes in the nucleus. |
| Immunogen | Epitope: between 642 and C-term |
| Other Names | AKAP-8; A-kinase anchor protein, 95kDa; A-kinase anchor protein 95 kDa; A-kinase anchor protein 8; AKAP-95; AKAP 95; A kinase (PRKA) anchor protein 8; AKAP95 |
| Gene, Accession # | Gene ID: 10270, Accession: NP_005849.1, UniProt: O43823 |
| Catalog # | IHC-00217-T |
| Price | $121 |
| Order / More Info | AKAP8/AKAP95 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
FORTIS LIFE SCIENCES
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