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Antigenic Specificity | AF6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 10 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-AF6 Antibody, Affinity Purified. AF6 was identified as part of a fusion with MLL (mixed lineage leukemia) in a t(6;11) genetic translocation. AF6 is also known as afadin (a splicing variant of AF6 found at adherins junction). AF6/afadin is an actin filament binding protein that binds to nectin at cadherin-based cell-cell adherens junctions and regulates cell-cell adhesion by mediating Ras signaling. |
Immunogen | Epitope: between 1475 and 1525 |
Other Names | l-afadin; protein AF-6; myeloid/lymphoid or mixed-lineage leukemia; translocated to, 4; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4; MLL-AF6; ALL1-fused gene from chromosome 6 protein; afadin; AF6; adherens junction formation factor; MLLT4 |
Gene, Accession # | Gene ID: 4301, Accession: BAA32484.1, UniProt: P55196 |
Catalog # | A302-199A-T |
Price | $121 |
Order / More Info | AF6 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |