alpha Actinin 4/ACTN4 Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | alpha Actinin 4/ACTN4 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, (presumed: rat, bovine) |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 10 µl |
| Concentration | 1000 µg/ml |
| Applications | WB, IP |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-alpha Actinin 4/ACTN4 Antibody, Affinity Purified. Alpha Actinin 4 / ACTN4 is an F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (Probable). It is probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation (PubMed:15772161). It is involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. It links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions (By similarity). alpha Actinin 4 / ACTN4 may also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA (PubMed:22351778) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O43707]. |
| Immunogen | Epitope: between 1 and 50 |
| Other Names | focal segmental glomerulosclerosis 1; non-muscle alpha-actinin 4; ACTININ-4; FSGS; alpha-actinin-4; FSGS1 |
| Gene, Accession # | Gene ID: 81, Accession: NP_004915.2, UniProt: O43707 |
| Catalog # | A304-768A-T |
| Price | $121 |
| Order / More Info | alpha Actinin 4/ACTN4 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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