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Antigenic Specificity | ATM |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 10 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Goat anti-ATM Antibody, Affinity Purified. Ataxia telangiectasia, mutated (ATM) is the gene responsible for the neurodegenerative disease ataxia telangiectasia (AT). AT is characterized by neurodegeneration, immune dysfunction, sensitivity to DNA damage, and cancer predisposition. ATM is a protein kinase central to the DNA damage response. In response to DNA double-strand breaks (DSBs), ATM initiates a signaling cascade that involves the phosphorylation of a multitude of substrates which include p53, BRCA1, p53 binding protein, CHK2, RAD9, RAD17, and MDM4. |
Immunogen | Epitope: between 2550 and 2600 |
Other Names | ATA; ATDC; TELO1; TEL1, telomere maintenance 1, homolog; TEL1; serine-protein kinase ATM; ATE; ATD; ataxia telangiectasia mutated; AT1; A-T mutated; AT mutated; ATC |
Gene, Accession # | Gene ID: 472, Accession: NP_000042.2, UniProt: Q13315 |
Catalog # | A300-136A-T |
Price | $121 |
Order / More Info | ATM Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |