HLA-DR/DP/DQ Antibody from FORTIS LIFE SCIENCES

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Antigenic SpecificityHLA-DR/DP/DQ
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
Isotypen/a
Formatpurified
Size10 µl (5+ tests)
Concentration250 µg/ml
ApplicationsWB, IHC, ICC
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DescriptionMouse anti-HLA-DR/DP/DQ Monoclonal Antibody [CR3/43]. In humans, Major Histocompatibility Locus (MHC) class II molecules are encoded by three different loci, HLA-DR, -DQ, and -DP, which display ?70% similarity to each other. Polymorphism is a notable feature of MHC class II genes. HLA-DR, HLA-DP, and HLA-DQ are heterodimeric cell surface glycoproteins comprised of an α (heavy) chain and a β (light) chain. They are expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. Variations in the HLA gene expression are crucial to graft survival.
ImmunogenCells from human tonsil
Other NamesMHC class II antigen DRA; HLA-DRA1; histocompatibility antigen HLA-DR alpha; HLA class II histocompatibility antigen, DR alpha chain
Gene, Accession #Gene ID: 3122, Accession: NP_061984.2, UniProt: P01903
Catalog #A500-034A-T
Price$127
Order / More InfoHLA-DR/DP/DQ Antibody from FORTIS LIFE SCIENCES
Product Specific Referencesn/a
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
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