PD-L1 Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | PD-L1 |
| Clone | monoclonal |
| Host Species | Recombinant Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | purified |
| Size | 20 µl (2 blots) |
| Concentration | 1000 µg/ml |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-PD-L1 Recombinant Monoclonal Antibody [BLR226K]. PD-L1 is an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. PD-L1 is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma [taken from NCBI Entrez Gene (Gene ID: 55193)]. |
| Immunogen | Epitope: residues 19-239 (ECD) |
| Other Names | Pdcd1lg1; B7 homolog 1; programmed cell death 1 ligand 1; PD-L1; Programmed death ligand 1; Pdl1; Pdcd1l1; PDCD1 ligand 1; CD antigen CD274; B7h1; A530045L16Rik; B7-H1 |
| Gene, Accession # | Gene ID: 60533, Accession: NP_068693.1, UniProt: Q9EP73 |
| Catalog # | A700-226-T |
| Price | $127 |
| Order / More Info | PD-L1 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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