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Antigenic Specificity | MIB2/Skeletrophin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 10 µl |
Concentration | 1000 µg/ml |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-MIB2/Skeletrophin Antibody, Affinity Purified. MIB2/Skeletrophin is an actin-binding protein that bears two MIB/HERC2 domains, a ZZ-type zinc-finger domain, nine ankyrin repeats, and two RING-finger domains. The C-terminal RING domain has been found to have E3 ubiquitin ligase activity that mediates ubiquitination of the intracellular regions of the Notch receptor and its ligands to regulate Notch signaling. MIB2/Skeletrophin appears to be important to muscle development and may function as a suppressor of melanoma invasion. |
Immunogen | Epitope: between 925 and 975 |
Other Names | zinc finger ZZ type with ankyrin repeat domain protein 1; ZZZ5; zinc finger, ZZ type with ankyrin repeat domain 1; skeletrophin; RING-type E3 ubiquitin transferase MIB2; novelzin; novel zinc finger protein; E3 ubiquitin-protein ligase MIB2; mindbomb homolog 2; mind bomb homolog 2; ZZANK1; putative NF-kappa-B-activating protein 002N |
Gene, Accession # | Gene ID: 142678, Accession: NP_543151.1, UniProt: Q96AX9 |
Catalog # | A301-414A-T |
Price | $121 |
Order / More Info | MIB2/Skeletrophin Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |