MCAK Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | MCAK |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 10 µl |
| Concentration | 250 µg/ml |
| Applications | IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-MCAK IHC Antibody, Affinity Purified. Kinesin activity has been linked to various cellular functions such as vesicle transport, mitotic spindle formation, chromosome segregation, chromosome congression, and cytokinesis. Structurally, all kinesins contain a motor domain with microtubule and nucleotide binding sites that utilize ATP to target cargo along microtubule filaments. MCAK (Mitotic Centromere-Associated Kinesin) is the founding member of kinesin-13 proteins. There are 3 independent genes coding for kinesin-13 proteins kif2a, kif2b, and kif2c (MCAK). Instead of functioning as a translocator of microtubules MCAK is a depolymerizer that is primarily responsible for releasing improper microtubule-kinetochore attachments during cell division. |
| Immunogen | Epitope: between 50 and 100 |
| Other Names | Knsl6; X83316; mitotic centromere-associated kinesin; MCAK; kinesin-like protein KIF2C; kinesin-like 6; 4930402F02Rik; ESTM5 |
| Gene, Accession # | Gene ID: 73804, Accession: NP_608301.3, UniProt: Q922S8 |
| Catalog # | IHC-00502-T |
| Price | $121 |
| Order / More Info | MCAK Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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