PKC-eta Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | PKC-eta |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 10 µl |
| Concentration | 1000 µg/ml |
| Applications | IP |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-PKC-eta Antibody, Affinity Purified. Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. PKC-eta is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. PKC-eta can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene [taken from NCBI Entrez Gene (Gene ID: 5583)]. |
| Immunogen | Epitope: between 300 and 350 |
| Other Names | PKCL; PKC-L; PRKCL; protein kinase C eta type; nPKC-eta |
| Gene, Accession # | Gene ID: 5583, Accession: NP_006246.2, UniProt: P24723 |
| Catalog # | A304-235A-T |
| Price | $121 |
| Order / More Info | PKC-eta Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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