MCSP Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | MCSP |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 10 µl |
| Concentration | 200 µg/ml |
| Applications | WB, IP |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-MCSP Antibody, Affinity Purified. Melanoma chondroitin sulfate proteoglycan (MCSP) is a cell-surface antigen expressed early in melanoma progression. It has been found to be involved in the spreading, invasion, and migration of human melanoma. MCSP influences melanoma behavior via the activation of the Cdc42 GTPase and phosphorylation of p130Cas. MCSP also activates signaling cascades involving FAK and ERK1/ERK2. In addition to its expression in melanoma cells, MCSP is also found in breast carcinomas, gliomas, neuroblastomas, and acute leukemias. MCSP is being considered as a target antigen for cancer immunotherapy. |
| Immunogen | Epitope: between 575 and 625 |
| Other Names | melanoma chondroitin sulfate proteoglycan; NG2; MSK16; melanoma-associated chondroitin sulfate proteoglycan; MCSPG; MCSP; HMW-MAA; chondroitin sulfate proteoglycan NG2; chondroitin sulfate proteoglycan 4 (melanoma-associated); chondroitin sulfate proteoglycan 4; MEL-CSPG |
| Gene, Accession # | Gene ID: 1464, Accession: NP_001888.2, UniProt: Q6UVK1 |
| Catalog # | A302-121A-T |
| Price | $121 |
| Order / More Info | MCSP Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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