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Antigenic Specificity | Ethenoadenosine |
Clone | 1G4 |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG2 |
Format | unconjugated |
Size | 20 µg |
Concentration | n/a |
Applications | Flow cytometry, Frozen sections, Immuno assays, Immuno precipitation, Western blot. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The reaction of chloroacetaldehyde (CAA) with DNA results in the formation of ethenoadenosine also known as 1,N6-ethenodeoxy-adenosine or etheno-A. CAA is formed through metabolization of for example vinyl chloride, a well established carcinogen. In RNA, after in vitro activation, etheno-A and etheno-C are the principle products of RNA damage. Etheno derivate formation may be highest in single-stranded DNA-regions. The monoclonal antibody 1G4 reacts with both the ribose and deoxyribose form of the adduct. The antibody is not cross reactive with non-modified DNA or the normal nucleotides. |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | HM5005-20UG |
Price | $157 |
Order / More Info | Ethenoadenosine Antibody from HYCULT BIOTECH |
Product Specific References | n/a |