L-FABP, Human Antibody from HYCULT BIOTECH

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Antigenic SpecificityL-FABP, Human
CloneL2B10
Host SpeciesMouse
Reactive Specieshuman, baboon, canine, human, rat, porcine
IsotypeIgG2b
Formatunconjugated
Size100 µg
Concentrationn/a
ApplicationsFrozen sections, Immuno assays, Paraffin sections, Western blot. RUO
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DescriptionThe monoclonal antibody L2B10 recognizes human liver fatty acid binding protein (L-FABP) of both natural and recombinant origin. The L-FABP protein is derived from the human FABP1 gene. FABPs are small intracellular proteins (~13-14 kDa) with a high degree of tissue specificity that bind long chain fatty acids. They are abundantly present in various cell types and play an important role in the intracellular utilization of fatty acids, transport and metabolism. There are at least nine distinct types of FABP, each showing a specific pattern of tissue expression. Due to its small size, FABP leaks rapidly out of ischemically damaged necrotic cells leading to a rise in serum levels. Ischemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. L-FABP is localized in the liver, kidney and intestinal epithelium. The monoclonal antibody L2B10 is useful to detect ischemic areas of human liver. Furthermore, the antibody can be used for the purification of human L-FABP.
Immunogenn/a
Other NamesHuman liver fatty acid binding protein, FABP1, Liver-type fatty acid-binding protein Gene name: FABP1, FABPL
Gene, Accession #n/a
Catalog #HM2049-100UG
Price$488
Order / More InfoL-FABP, Human Antibody from HYCULT BIOTECH
Product Specific Referencesn/a
HYCULT BIOTECH
HYCULT BIOTECH
HYCULT BIOTECH
Frontstraat 2a
5405 PB Uden THE NETHERLANDS
P: +31 (0)413 251335
F: +31 (0)413 248353

info@hycultbiotech.com

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