CD46, Mouse Antibody from HYCULT BIOTECH
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| Antigenic Specificity | CD46, Mouse |
| Clone | MM10 |
| Host Species | Rat |
| Reactive Species | mouse, rat |
| Isotype | IgG2a |
| Format | unconjugated |
| Size | 20 µg |
| Concentration | n/a |
| Applications | Flow cytometry, Frozen sections, Immuno assays, Immuno fluorescence, Western blot. RUO |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The monoclonal antibody MM10 recognizes membrane cofactor protein (MCP), also known as CD46. MCP is a type I membrane glycoprotein that consists of four isoforms i.e. two C-isoforms (51-58 kDa) and two BC isoforms (59-68 kDa) which arise by alternative splicing of a single CD46 gene. Membrane cofactor protein is expressed on every cell and tissue, with the exception of erythrocytes. Membrane cofactor protein serves to down-regulate the activation of complement on host tissue. MCP is a cofactor for factor 1-mediated cleavage of C3b and C4b and this way serves to protect the host cell against autologous attack. MCP is a receptor for several pathogens including measles virus, group A Streptococcus pyogenes and pathogenic Neisseria. |
| Immunogen | Mouse CD46-human Fc fusion protein |
| Other Names | MCP, CD46, Trophoblast leukocyte common antigen, TLX, measles virus receptor |
| Gene, Accession # | n/a |
| Catalog # | HM1118-20UG |
| Price | $157 |
| Order / More Info | CD46, Mouse Antibody from HYCULT BIOTECH |
| Product Specific References | n/a |
HYCULT BIOTECH
HYCULT BIOTECH
Frontstraat 2a
5405 PB Uden THE NETHERLANDS
P: +31 (0)413 251335
F: +31 (0)413 248353
info@hycultbiotech.com
https://www.hycultbiotech.com
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