Nectin-2, Human Antibody from HYCULT BIOTECH
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| Antigenic Specificity | Nectin-2, Human |
| Clone | TX31 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 20 µg |
| Concentration | n/a |
| Applications | Flow cytometry, Functional studies, Western blot. RUO |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Monoclonal antibody clone Tx31 recognizes human Nectin-2. Nectin-2 was initially discovered as a poliovirus receptor-related protein (PRR2). Nectins are immunoglobulin-like transmembrane cell adhesion molecules expressed in various cell types. The nectin family consist of 4 members. Nectin-1/2/3 are expressed in cells like fibroblast, epithelial cells and neurons. Nectin-2 is also expressed in hematopoietic cells and spermatids. Nectins, which are ca2+-independent immunoglobulin like molecules, regulate cell-cell adhesions. They are involved in different type of disease like viral infection, autism, Alzheimer and cancer. Nectin-2 is believed to form homodimers or heterodimers in their function for cell adhesion. It forms an immune costimulatory function together with DNAM-1 thereby regulating both NK and CTL function. |
| Immunogen | Recombinant protein |
| Other Names | CD112, Herpes virus entry mediator B, Herpesvirus entry mediator B, HveB, Nectin cell adhesion molecule 2, Poliovirus receptor-related protein 2. |
| Gene, Accession # | n/a |
| Catalog # | HM2393-20UG |
| Price | $157 |
| Order / More Info | Nectin-2, Human Antibody from HYCULT BIOTECH |
| Product Specific References | n/a |
HYCULT BIOTECH
HYCULT BIOTECH
Frontstraat 2a
5405 PB Uden THE NETHERLANDS
P: +31 (0)413 251335
F: +31 (0)413 248353
info@hycultbiotech.com
https://www.hycultbiotech.com
Profile of HYCULT BIOTECH