Desmoglein-1, Human Antibody from HYCULT BIOTECH

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Antigenic SpecificityDesmoglein-1, Human
Clone27B2
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatunconjugated
Size100 µg
Concentrationn/a
ApplicationsFlow cytometry, Frozen sections, Immuno fluorescence, Immuno precipitation, Western blot. RUO
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DescriptionDesmoglein 1 is a member of the desmosomal cadherin family that comprise the desmogleins and desmocollins. Desmosomes are cell-cell junctions in most epithelial cells and serve to link the intermediate filament cytoskeletons of adjacent cells. Within the desmosome the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Desmoglein 1 is synthesized exclusively in the suprabasal layers. Intact and functionally active desmoglein 1 is essential to epidermal integrity. The monoclonal antibody 27B2 reacts with the 165 kDa desmoglein 1 protein. Furthermore it is not cross reactive with desmoglein 2 or desmoglein 3.
Immunogenn/a
Other Namesn/a
Gene, Accession #n/a
Catalog #HM2113-100UG
Price$538
Order / More InfoDesmoglein-1, Human Antibody from HYCULT BIOTECH
Product Specific Referencesn/a
HYCULT BIOTECH
HYCULT BIOTECH
HYCULT BIOTECH
Frontstraat 2a
5405 PB Uden THE NETHERLANDS
P: +31 (0)413 251335
F: +31 (0)413 248353

info@hycultbiotech.com

https://www.hycultbiotech.com

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