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Antigenic Specificity | JAM-A, Mouse |
Clone | BV12 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a |
Format | unconjugated |
Size | 20 µg |
Concentration | n/a |
Applications | Flow cytometry, Immuno fluorescence, Immuno precipitation, Western blot. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The monoclonal antibody BV12 recognizes junctional adhesion molecule-A (JAM-A), also known as JAM-1 and the mouse platelet F11-Receptor (F11R), is a cell adhesion molecule (CAM). JAM-A is a member of the immunoglobulin superfamily found on the surface of mouse platelets and at intercellular junctions of endothelial cells and epithelial cells. JAM-A belongs together with JAM-B (VE-JAM or JAM-3) and JAM-C (JAM-2) to a family of adhesion proteins with a V-C2 immunoglobulin domain organization. JAM plays an important role in tight junctions where it is involved in cell-to-cell adhesion through homophilic interaction. It codistributes with other tight junction components as ZO-1, 7H6 antigen, cingulin and occludin. In human JAM-A plays a role in platelet aggregation, secretion, adhesion and spreading. |
Immunogen | n/a |
Other Names | JAM-1, F11R |
Gene, Accession # | n/a |
Catalog # | HM1050-20UG |
Price | $157 |
Order / More Info | JAM-A, Mouse Antibody from HYCULT BIOTECH |
Product Specific References | n/a |