TNF-alpha, Human Antibody from HYCULT BIOTECH

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Antigenic SpecificityTNF-alpha, Human
CloneT1
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
FormatProtein G purified
Size20 µg
Concentrationn/a
ApplicationsFlow cytometry, Functional studies, Immuno assays, Western blot. RUO
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DescriptionThe antibody reacts with free soluble (17 kDa) and membrane (26 kDa) human TNF-alpha. The antibody inhibits the biological activity of both forms. It does not react with receptor bound TNF-alpha. It can be a useful tool to discriminate between the membrane form of TNF expressed on producer cells and the proteolytically cleaved, soluble TNF-alpha bound to its cognate cell membrane receptors (TNF-RI and TNF-RII). For this purpose we recommend to use this antibody in combination with the anti-TNF-alpha antibody HM2026, which recognizes soluble, membrane and receptor bound TNF-alpha.
ImmunogenBALB/c mice with huTNF, fusion of spleen cells with NSO myeloma cells
Other NamesTumor necrosis factor, Cachectin, Tumor necrosis factor ligand superfamily member 2, Tumor necrosis factor, membrane form, C-domain 2, Tumor necrosis factor, soluble form Gene name: TNFA, TNFSF2
Gene, Accession #n/a
Catalog #HM2024-20UG
Price$157
Order / More InfoTNF-alpha, Human Antibody from HYCULT BIOTECH
Product Specific Referencesn/a
HYCULT BIOTECH
HYCULT BIOTECH
HYCULT BIOTECH
Frontstraat 2a
5405 PB Uden THE NETHERLANDS
P: +31 (0)413 251335
F: +31 (0)413 248353

info@hycultbiotech.com

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