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Antigenic Specificity | TNF-alpha, Human |
Clone | T1 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein G purified |
Size | 20 µg |
Concentration | n/a |
Applications | Flow cytometry, Functional studies, Immuno assays, Western blot. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody reacts with free soluble (17 kDa) and membrane (26 kDa) human TNF-alpha. The antibody inhibits the biological activity of both forms. It does not react with receptor bound TNF-alpha. It can be a useful tool to discriminate between the membrane form of TNF expressed on producer cells and the proteolytically cleaved, soluble TNF-alpha bound to its cognate cell membrane receptors (TNF-RI and TNF-RII). For this purpose we recommend to use this antibody in combination with the anti-TNF-alpha antibody HM2026, which recognizes soluble, membrane and receptor bound TNF-alpha. |
Immunogen | BALB/c mice with huTNF, fusion of spleen cells with NSO myeloma cells |
Other Names | Tumor necrosis factor, Cachectin, Tumor necrosis factor ligand superfamily member 2, Tumor necrosis factor, membrane form, C-domain 2, Tumor necrosis factor, soluble form Gene name: TNFA, TNFSF2 |
Gene, Accession # | n/a |
Catalog # | HM2024-20UG |
Price | $157 |
Order / More Info | TNF-alpha, Human Antibody from HYCULT BIOTECH |
Product Specific References | n/a |